'Pain in a dish': Scientists create living model of human nerve cells.
"Harvard University researchers said they have generated the human nerve cells that normally send painful stimuli to the brain by reprogramming ordinary skin cells experimentally so that they develop into fully mature, adult pain neurons.
The result is “pain in a dish”, which they believe could be used to discover new kinds of analgesics and other forms of pain relief, as well as helping to find out why some people are more prone to feeling chronic pain than others."
http://www.independent.co.uk/news/science/pain-in-a-dish-scientists-create-living-model-of-human-nerve-cells-9880408.html
Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ. Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts. Nat Neurosci 2014 Nov;advance online publication Available from: http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3886.html
"Harvard University researchers said they have generated the human nerve cells that normally send painful stimuli to the brain by reprogramming ordinary skin cells experimentally so that they develop into fully mature, adult pain neurons.
The result is “pain in a dish”, which they believe could be used to discover new kinds of analgesics and other forms of pain relief, as well as helping to find out why some people are more prone to feeling chronic pain than others."
http://www.independent.co.uk/news/science/pain-in-a-dish-scientists-create-living-model-of-human-nerve-cells-9880408.html
Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ. Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts. Nat Neurosci 2014 Nov;advance online publication Available from: http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3886.html
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